Disclaimer The opinions expressed herein are my own personal opinions and do not represent my employer's view in anyway.
I've been using a variety of collabortaion tools lately that have drastically cut down on the number of emails I send and receive each day.
For example, I've been using Groove to exchange PowerPoint decks with my colleagues. It's great for large files since only the diffs get synchronized and I always have the files I need locally. And Groove syncs with SharePoint, so when I get my updates completed, everyone within Microsoft can find my new deck via SharePoint's enterprise search.
I've also been using Office Communicator to IM with folks both inside and outside of Microsoft rather than volleying a half-dozen emails back and forth.
But I think I still get too many emails, as is evident by my most recently received message...but at least I still have 1MB of space left.